Protein Technology

Broad experience with expression and purification of challenging and membrane proteins to generate high quality proteins for various applications.

Scientific Excellence in Protein Generation

Our team has long-standing experience in the design of appropriate constructs for multi-domain and membrane proteins, followed by expression and purification to achieve high-quality proteins for crystallization and biophysical applications.

We offer a comprehensive portfolio of biophysical methods

We have a holistic expertise in the application of biophysical methods for various applications including

  • Surface Plasmon Resonance (SPR)
  • (cellular) Thermal Shift Assays(TSA)
  • Isothermal Titration Calorimetry (ITC)
  • Differential Scanning Fluorimetry (DSF)
  • Microscale Thermophoresis (MST)

We analyse our proteins using mass spectrometry

We apply mass spectrometry-based methods to identify covalent binders to protein targets, to analyse binding of lead molecules to protein targets using native MS, and to assess the quality of protein batches.