Preclinical Compound Profiling

Our expertise is the identification of ADMET liabilities of lead structures with the goal to guide a focused and fast optimization of lead structures towards a viable clinical candidate.

Our versatile team supports the optimisation of ADMET properties of lead structures and drug candidates by using state-of-the-art medium and high through-put in vitro DMPK and genotoxicological Assays.

We perform in vivo DMPK studies in rodents, using various administration routes and dosing schedules according to the project needs.

We offer versatile Mass Spectrometry (MS) capabilities, from targeted drug quantitation to unknown metabolite structure elucidation  and molecular distribution in tissues.

Our team is focused in keeping and providing the animals necessary for scientific experimentation in state of the art housing and in healthy condition.